ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
种属
Homo sapiens (Human)
性质
Recombinant
内毒素水平
Please contact with the lab for this information.
纯度
>90% as determined by SDS-PAGE.
预测分子量
36.94 kDa
状态
Lyophilized
保存溶液
Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.
Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
重悬
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
运输
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
稳定性和存储
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名
ATA1, Amino acid transporter A1, N-system amino acid transporter 2, NAT2, SAT1, SLC38A1, SNAT1, Sodium-coupled neutral amino acid symporter 1, Solute carrier family 38 member 1, System A amino acid transporter 1, System N amino acid transporter 1
背景
Sodium-coupled neutral amino acid symporter 1 is a ~54 kDa protein. Symporter that cotransports short-chain neutral amino acids and sodium ions from the extracellular to the intracellular side of the cell membrane. The transport is elctrogenic, pH dependent and driven by the Na(+) electrochemical gradient. Participates in the astroglia-derived glutamine transport into GABAergic interneurons for neurotransmitter GABA de novo synthesis. May also contributes to amino acid transport in placental trophoblasts. Also regulates synaptic plasticity.
1. Wang, H. et al. (2000) Biochemical and biophysical research communications 273, 1175-9. PMID: 10891391
2. Desforges, M. et al. (2010) Biochemical and biophysical research communications 398, 130-4. PMID: 20599747
3. Nelson, DM. et al. (2003) American journal of physiology. Cell physiology 284, C310-5. PMID: 12388062
