Human CD121b/IL1R2/IL-2R beta Recombinant Protein (C-Fc) (HB066021)
概述
图片
参考文献
产品说明书
概述
货号
HB066021
品牌
abinScience
描述
Recombinant Human CD121b/IL1R2/IL-2R beta Protein, C-Fc (HB066021) expressed in Mammalian Cells, spanning Met1-Glu343. Purity: >90% by SDS-PAGE.
Highlights
●Fc Fusion — Enhanced stability with Protein A/G purification compatibility.
●Mammalian Expression — Proper folding and native glycosylation.
●High Purity — >90% purity verified by SDS-PAGE.
表达系统
Mammalian cells
Accession号
P27930
蛋白长度
Met1-Glu343
应用
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
种属
Homo sapiens (Human)
性质
Recombinant
内毒素水平
Please contact with the lab for this information.
纯度
>90% as determined by SDS-PAGE.
预测分子量
65.62 kDa
状态
Lyophilized
保存溶液
Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.
Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
重悬
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
运输
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
稳定性和存储
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名
CD121 antigen-like family member B, CD121b, CDw121b, IL-1 type II receptor, IL-1R-2, IL-1R-beta, IL-1RT-2, IL-1RT2, IL1R2, IL1RB, Interleukin-1 receptor beta, Interleukin-1 receptor type 2, Interleukin-1 receptor type 2, membrane form, Interleukin-1 receptor type 2, soluble form, Interleukin-1 receptor type II, mIL-1R2, mIL-1RII, sIL-1R2, sIL-1RII
背景
Interleukin-1 receptor type 2 is a ~45 kDa protein. Non-signaling receptor for IL1A, IL1B and IL1RN. Reduces IL1B activities. Serves as a decoy receptor by competitive binding to IL1B and preventing its binding to IL1R1. Also modulates cellular response through non-signaling association with IL1RAP after binding to IL1B. IL1R2 (membrane and secreted forms) preferentially binds IL1B and poorly IL1A and IL1RN.
