Human/Mouse/Rat GABRA1 Recombinant Protein (N-His) (HB280012)

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概述

货号	HB280012
品牌	abinScience
描述	Recombinant Human BABRA1 Protein, N-His (HB280012) expressed in E. coli, spanning Arg64-Lys249. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
表达系统	E. coli
Accession号	P14867, P62812, P62813
蛋白长度	Arg64-Lys249
应用	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
种属	Homo sapiens (Human)
性质	Recombinant
内毒素水平	Please contact with the lab for this information.
纯度	>90% as determined by SDS-PAGE.
预测分子量	23.77 kDa
状态	Lyophilized
保存溶液	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
重悬	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
运输	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名	GABA(A) receptor subunit alpha-1, GABAAR subunit alpha-1, GABRA1, Gamma-aminobutyric acid receptor subunit alpha-1
背景	Gamma-aminobutyric acid receptor subunit alpha-1 is a ~51 kDa protein. Alpha subunit of the heteropentameric ligand-gated chloride channel gated by Gamma-aminobutyric acid (GABA), a major inhibitory neurotransmitter in the brain. GABA-gated chloride channels, also named GABA(A) receptors (GABAAR), consist of five subunits arranged around a central pore and contain GABA active binding site(s) located at the alpha and beta subunit interface(s). When activated by GABA, GABAARs selectively allow the flow of chloride anions across the cell membrane down their electrochemical gradient. Alpha-1/GABRA1-containing GABAARs are largely synaptic. Chloride influx into the postsynaptic neuron following GABAAR opening decreases the neuron ability to generate a new action potential, thereby reducing nerve transmission. 1. Fuchs, C. et al. (2013) The European journal of neuroscience 38, 3146-58. PMID: 23909897 2. Brown, LE. et al. (2014) Journal of visualized experiments : JoVE, e52115. PMID: 25489750 3. Zhu, S. et al. (2018) Nature 559, 67-72. PMID: 29950725 4. Laverty, D. et al. (2019) Nature 565, 516-520. PMID: 30602789
Note	For research use only

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参考文献

产品说明书

Human/Mouse/Rat GABRA1 Recombinant Protein (N-His).pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Human/Mouse/Rat GABRA1 Recombinant Protein (N-His) (HB280012)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Human/Mouse/Rat GABRA1 Recombinant Protein (N-His) (HB280012)

概述

图片

参考文献

产品说明书

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