Mouse IL-4R alpha Recombinant Protein (C-Fc) (MB732011)
概述
图片
参考文献
产品说明书
概述
货号
MB732011
品牌
abinScience
描述
Recombinant Mouse CD124/IL4R Protein, C-Fc (MB732011) expressed in Mammalian Cells, spanning Met1-Arg233. Purity: >90% by SDS-PAGE.
Highlights
●Fc Fusion — Enhanced stability with Protein A/G purification compatibility.
●Mammalian Expression — Proper folding and native glycosylation.
●High Purity — >90% purity verified by SDS-PAGE.
表达系统
Mammalian cells
Accession号
P16382
蛋白长度
Met1-Arg233
应用
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
种属
Mus musculus (Mouse)
性质
Recombinant
内毒素水平
Please contact with the lab for this information.
纯度
>90% as determined by SDS-PAGE.
预测分子量
53.34 kDa
状态
Lyophilized
保存溶液
Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.
Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
重悬
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
运输
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
稳定性和存储
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Interleukin-4 receptor subunit alpha is a ~87 kDa protein. Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic inflammation. In certain cell types, can signal through activation of insulin receptor substrates, IRS1/IRS2.
Note
For research use only
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Bioactivity
Detected by REGN1103 (Catalog No: MB732013) in indirect ELISA.
Bioactivity
Immobilized MB732011 Mouse CD124/IL4R Recombinant Protein (C-Fc) at 2 μg/mL(100 μL/well) can bind MY457011 Mouse IL4 Recombinant Protein (N-mFc), the EC 50 is 127 ng/mL.
Bioactivity
Immobilized MY457011 Mouse IL4 Recombinant Protein (N-mFc) at 2 μg/mL(100 μL/well) can bind MB732011 Mouse CD124/IL4R Recombinant Protein (C-Fc), the EC 50 is 156 ng/mL.
