Mouse IGFBP2 Recombinant Protein (C-His) (MB875011)

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1mg

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概述
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概述

货号	MB875011
品牌	abinScience
描述	Recombinant Mouse IGFBP2 Protein, C-His (MB875011) expressed in Mammalian Cells, spanning Met1-Gln305. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●Mammalian Expression — Proper folding and native glycosylation. ●High Purity — >90% purity verified by SDS-PAGE.
表达系统	Mammalian cells
Accession号	P47877
蛋白长度	Met1-Gln305
应用	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
种属	Mus musculus (Mouse)
性质	Recombinant
内毒素水平	Remove endotoxin and sterilization is required for cell assay.
纯度	>90% as determined by SDS-PAGE.
预测分子量	33.81 kDa
状态	Lyophilized
保存溶液	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
重悬	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
运输	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名	BP2, IBP-2, IBP2, IGF-binding protein 2, IGFBP-2, IGFBP2, Insulin-like growth factor-binding protein 2
背景	Insulin-like growth factor-binding protein 2 is a ~32 kDa protein. Multifunctional protein that plays a critical role in regulating the availability of IGFs such as IGF1 and IGF2 to their receptors and thereby regulates IGF-mediated cellular processes including proliferation, differentiation, and apoptosis in a cell-type specific manner. Functions coordinately with receptor protein tyrosine phosphatase beta/PTPRB and the IGF1 receptor to regulate IGF1-mediated signaling by stimulating the phosphorylation of PTEN leading to its inactivation and AKT1 activation. Plays a positive role in cell migration via interaction with integrin alpha5/ITGA5 through an RGD motif. Additionally, interaction with ITGA5/ITGB1 enhances the adhesion of endothelial progenitor cells to endothelial cells. Upon mitochondrial damage, facilitates apoptosis with ITGA5 of podocytes, and then activates the phosphorylation of focal adhesion kinase (FAK)-mediated mitochondrial injury. 1. DeMambro, VE. et al. (2008) Endocrinology 149, 2051-61. PMID: 18276763 2. Xi, G. et al. (2016) Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 31, 1300-14. PMID: 26773517
Note	For research use only

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SDS-PAGE

SDS-PAGE for Mouse IGFBP2 Recombinant Protein (C-His)

参考文献

产品说明书

Mouse IGFBP2 Recombinant Protein (C-His).pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Mouse IGFBP2 Recombinant Protein (C-His) (MB875011)

概述

图片

参考文献

产品说明书

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重组蛋白

抗体

试剂盒

实验相关试剂

Mouse IGFBP2 Recombinant Protein (C-His) (MB875011)

概述

图片

参考文献

产品说明书

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