Mouse IL-11 Recombinant Protein (N-His) (MB978012)

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概述

货号	MB978012
品牌	abinScience
描述	Recombinant Mouse IL11 Protein, N-His (MB978012) expressed in E. coli, spanning Gly23-Leu199. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
表达系统	E. coli
Accession号	P47873
蛋白长度	Gly23-Leu199
应用	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
种属	Mus musculus (Mouse)
性质	Recombinant
内毒素水平	Please contact with the lab for this information.
纯度	>90% as determined by SDS-PAGE.
预测分子量	21.35 kDa
状态	Lyophilized
保存溶液	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
重悬	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
运输	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名	AGIF, Adipogenesis inhibitory factor, IL-11, IL11, Interleukin-11, Oprelvekin
背景	Interleukin-11 is a ~21 kDa protein. Cytokine that stimulates the proliferation of hematopoietic stem cells and megakaryocyte progenitor cells and induces megakaryocyte maturation resulting in increased platelet production. Also promotes the proliferation of hepatocytes in response to liver damage. Binding to its receptor formed by IL6ST and either IL11RA1 or IL11RA2 activates a signaling cascade that promotes cell proliferation, also in the context of various cancers. Signaling leads to the activation of intracellular protein kinases and the phosphorylation of STAT3. The interaction with the membrane-bound IL11RA and IL6ST stimulates 'classic signaling', whereas the binding of IL11 and soluble IL11RA to IL6ST stimulates 'trans-signaling'. 1. Morris, JC. et al. (1996) Experimental hematology 24, 1369-76. PMID: 8913282 2. Nishina, T. et al. (2012) Science signaling 5, ra5. PMID: 22253262 3. Barton, VA. et al. (1999) The Journal of biological chemistry 274, 5755-61. PMID: 10026196 4. Putoczki, TL. et al. (2013) Cancer cell 24, 257-71. PMID: 23948300
Note	For research use only

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参考文献

产品说明书

Mouse IL-11 Recombinant Protein (N-His).pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

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质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Mouse IL-11 Recombinant Protein (N-His) (MB978012)

概述

图片

参考文献

产品说明书

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重组蛋白

抗体

试剂盒

实验相关试剂

Mouse IL-11 Recombinant Protein (N-His) (MB978012)

概述

图片

参考文献

产品说明书

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