ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
种属
Homo sapiens (Human)
性质
Recombinant
内毒素水平
Please contact with the lab for this information.
纯度
>90% as determined by SDS-PAGE.
预测分子量
23.61 kDa
状态
Lyophilized
保存溶液
Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.
Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
重悬
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
运输
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
稳定性和存储
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名
C1orf121, DESI2, DeSI-2, Desumoylating isopeptidase 2, Deubiquitinase DESI2, EC:3.1.2.22, EC:3.4.19.12, FAM152A, PPPDE peptidase domain-containing protein 1, PPPDE1, Palmitoyl protein thioesterase DESI2, Protein FAM152A, S-depalmitoylase DESI2
背景
Deubiquitinase DESI2 is a ~21 kDa protein. Has deubiquitinating activity towards 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains. Deubiquitinates 'Lys-48'-linked polyubiquitination of RPS7 leading to its stabilization. Exhibits palmitoyl protein thioesterase (S-depalmitoylation) activity towards synthetic substrates 4-methylumbelliferyl-6-S-palmitoyl-beta-D-glucopyranoside and S-depalmitoylation probe 5 (DPP-5).
1. Xie, X. et al. (2017) Biochemical and biophysical research communications 488, 291-296. PMID: 28483520
2. Luebben, AV. et al. (2022) Science advances 8, eabj8633. PMID: 35427157
