

| 货号 | HC745012 |
|---|---|
| 品牌 | abinScience |
| 描述 |
Recombinant Human TBX2 Protein, N-His (HC745012) expressed in E. coli, spanning Glu102-Gly284. Purity: >90% by SDS-PAGE.
Highlights
|
| 表达系统 | E. coli |
| Accession号 | Q13207 |
| 蛋白长度 | Glu102-Gly284 |
| 应用 | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 种属 | Homo sapiens (Human) |
| 性质 | Recombinant |
| 内毒素水平 | Please contact with the lab for this information. |
| 纯度 | >90% as determined by SDS-PAGE. |
| 预测分子量 | 23.59 kDa |
| 状态 | Lyophilized |
| 保存溶液 | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 重悬 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 运输 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 别名 | T-box protein 2, T-box transcription factor TBX2, TBX2 |
| 背景 | T-box transcription factor TBX2 is a ~75 kDa protein. Transcription factor which acts as a transcriptional repressor. May also function as a transcriptional activator. Binds to the palindromic T site 5'-TTCACACCTAGGTGTGAA-3' DNA sequence, or a half-site, which are present in the regulatory region of several genes. Required for cardiac atrioventricular canal formation. May cooperate with NKX2.5 to negatively modulate expression of NPPA/ANF in the atrioventricular canal. 1. Jacobs, JJ. et al. (2000) Nature genetics 26, 291-9. PMID: 11062467 2. Sinha, S. et al. (2000) Gene 258, 15-29. PMID: 11111039 3. Lingbeek, ME. et al. (2002) The Journal of biological chemistry 277, 26120-7. PMID: 12000749 4. Wang, B. et al. (2012) PloS one 7, e41355. PMID: 22844464 5. Reinhardt, S. et al. (2019) Cellular and molecular life sciences : CMLS 76, 1005-1025. PMID: 30599067 6. Liu, N. et al. (2018) Human molecular genetics 27, 2454-2465. PMID: 29726930 7. Martin, N. et al. (2012) The EMBO journal 31, 95-109. PMID: 22002537 |
| Note | For research use only |

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