Human CD158g Recombinant Protein (C-Fc) (HC800011)
概述
图片
参考文献
产品说明书
概述
货号
HC800011
品牌
abinScience
描述
Recombinant Human CD158g Protein, C-Fc (HC800011) expressed in Mammalian Cells, spanning His22-His245. Purity: >90% by SDS-PAGE.
Highlights
●Fc Fusion — Enhanced stability with Protein A/G purification compatibility.
●Mammalian Expression — Proper folding and native glycosylation.
●High Purity — >90% purity verified by SDS-PAGE.
表达系统
Mammalian cells
Accession号
Q14953
蛋白长度
His22-His245
应用
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
种属
Homo sapiens (Human)
性质
Recombinant
内毒素水平
Please contact with the lab for this information.
纯度
>90% as determined by SDS-PAGE.
预测分子量
53.07 kDa
状态
Lyophilized
保存溶液
Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.
Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
重悬
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
运输
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
稳定性和存储
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名
CD158 antigen-like family member G, CD158G, CD158g, KIR2DS5, Killer cell immunoglobulin-like receptor 2DS5, NKAT-9, NKAT9, Natural killer-associated transcript 9
背景
Killer cell immunoglobulin-like receptor 2DS5 is a ~33 kDa protein. Activating natural killer (NK) receptor that recognizes C2 epitopes of HLA-C alleles. Bridging the innate and adaptive immune systems, NK cells express a number of cell surface receptors which either inhibit or stimulate their cytotoxicity. Able to activate NK cells citotoxicity and cytokine production such as IFNG. Receptor functions are attenuated even lost in some alleles, such as KIR2DS5*002 represented in this entry.
1. Della Chiesa, M. et al. (2008) European journal of immunology 38, 2284-9. PMID: 18624290
2. Steiner, NK. et al. (2008) Immunogenetics 60, 655-67. PMID: 18682925
3. Blokhuis, JH. et al. (2017) Immunity, inflammation and disease 5, 461-468. PMID: 28685972
4. Steiner, NK. et al. (2014) Human immunology 75, 124-8. PMID: 24269691
