

| 货号 | HC809012 |
|---|---|
| 品牌 | abinScience |
| 描述 |
Recombinant Human MARCKSL1 Protein, N-GST & C-His (HC809012) expressed in E. coli, spanning Gly2-Glu195. Purity: >90% by SDS-PAGE.
Highlights
|
| 表达系统 | E. coli |
| Accession号 | P49006 |
| 蛋白长度 | Gly2-Glu195 |
| 应用 | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 种属 | Homo sapiens (Human) |
| 性质 | Recombinant |
| 内毒素水平 | Please contact with the lab for this information. |
| 纯度 | >90% as determined by SDS-PAGE. |
| 预测分子量 | 47.58 kDa |
| 状态 | Lyophilized |
| 保存溶液 | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 重悬 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 运输 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 别名 | MARCKS-like protein 1, MARCKS-related protein, MARCKSL1, MLP, MRP, Mac-MARCKS, MacMARCKS, Macrophage myristoylated alanine-rich C kinase substrate |
| 背景 | MARCKS-related protein is a ~19 kDa protein. Controls cell movement by regulating actin cytoskeleton homeostasis and filopodium and lamellipodium formation. When unphosphorylated, induces cell migration. When phosphorylated by MAPK8, induces actin bundles formation and stabilization, thereby reducing actin plasticity, hence restricting cell movement, including neuronal migration. May be involved in coupling the protein kinase C and calmodulin signal transduction systems. 1. Björkblom, B. et al. (2012) Molecular and cellular biology 32, 3513-26. PMID: 22751924 |
| Note | For research use only |

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