Human CCNT1 Recombinant Protein (N-His) (HC948012)

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1mg

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概述

货号	HC948012
品牌	abinScience
描述	Recombinant Human CCNT1 Protein, N-His (HC948012) expressed in E. coli, spanning Met1-Ser290. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
表达系统	E. coli
Accession号	O60563
蛋白长度	Met1-Ser290
应用	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
种属	Homo sapiens (Human)
性质	Recombinant
内毒素水平	Please contact with the lab for this information.
纯度	>90% as determined by SDS-PAGE.
预测分子量	35.52 kDa
状态	Lyophilized
保存溶液	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
重悬	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
运输	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名	CCNT1, CycT1, Cyclin-T, Cyclin-T1
背景	Cyclin-T1 is a ~80 kDa protein. Regulatory subunit of the cyclin-dependent kinase pair (CDK9/cyclin-T1) complex, also called positive transcription elongation factor B (P-TEFb), which facilitates the transition from abortive to productive elongation by phosphorylating the CTD (C-terminal domain) of the large subunit of RNA polymerase II (RNA Pol II). Required to activate the protein kinase activity of CDK9: acts by mediating formation of liquid-liquid phase separation (LLPS) that enhances binding of P-TEFb to the CTD of RNA Pol II. 1. Jang, MK. et al. (2005) Molecular cell 19, 523-34. PMID: 16109376 2. Yang, Z. et al. (2005) Molecular cell 19, 535-45. PMID: 16109377 3. Ghosh, K. et al. (2018) Cell reports 24, 2141-2154.e6. PMID: 30134174 4. Fu, H. et al. (2022) Nature cell biology 24, 513-525. PMID: 35393539 5. Lu, H. et al. (2018) Nature 558, 318-323. PMID: 29849146
Note	For research use only

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SDS-PAGE

SDS-PAGE for Human CCNT1 Recombinant Protein (N-His)

参考文献

产品说明书

Human CCNT1 Recombinant Protein (N-His).pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Human CCNT1 Recombinant Protein (N-His) (HC948012)

概述

图片

参考文献

产品说明书

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重组蛋白

抗体

试剂盒

实验相关试剂

Human CCNT1 Recombinant Protein (N-His) (HC948012)

概述

图片

参考文献

产品说明书

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