ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
种属
Homo sapiens (Human)
性质
Recombinant
内毒素水平
Please contact with the lab for this information.
纯度
>90% as determined by SDS-PAGE.
预测分子量
22.07 kDa
状态
Lyophilized
保存溶液
Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.
Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
重悬
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
运输
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
稳定性和存储
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名
Alpha-crystallin A chain, Alpha-crystallin A(1-162), Alpha-crystallin A(1-168), Alpha-crystallin A(1-172), CRYA1, CRYAA, HSPB4, Heat shock protein beta-4, Heat shock protein family B member 4, HspB4
背景
Alpha-crystallin A chain is a ~19 kDa protein. Contributes to the transparency and refractive index of the lens. In its oxidized form (absence of intramolecular disulfide bond), acts as a chaperone, preventing aggregation of various proteins under a wide range of stress conditions. Required for the correct formation of lens intermediate filaments as part of a complex composed of BFSP1, BFSP2 and CRYAA.
1. Richter, L. et al. (2008) American journal of medical genetics. Part A 146A, 833-42. PMID: 18302245
2. Murugesan, R. et al. (2007) Molecular vision 13, 2301-9. PMID: 18199971
3. Bhagyalaxmi, SG. et al. (2009) Biochimica et biophysica acta 1792, 974-81. PMID: 19595763
4. Nagaraj, RH. et al. (2012) Biochimica et biophysica acta 1822, 120-9. PMID: 22120592
