Human USP51 Recombinant Protein (N-His) (HD003012)

价格: --

规格：

50ug
100ug
1mg

数量：

联系我们

一键复制产品信息

概述
图片
参考文献
产品说明书

概述

货号	HD003012
品牌	abinScience
描述	Recombinant Human USP51 Protein, N-His (HD003012) expressed in E. coli, spanning Asn370-Asp711. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
表达系统	E. coli
Accession号	Q70EK9
蛋白长度	Asn370-Asp711
应用	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
种属	Homo sapiens (Human)
性质	Recombinant
内毒素水平	Please contact with the lab for this information.
纯度	>90% as determined by SDS-PAGE.
预测分子量	41.09 kDa
状态	Lyophilized
保存溶液	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
重悬	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
运输	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名	Deubiquitinating enzyme 51, EC:3.4.19.12, USP51, Ubiquitin carboxyl-terminal hydrolase 51, Ubiquitin thioesterase 51, Ubiquitin-specific-processing protease 51
背景	Ubiquitin carboxyl-terminal hydrolase 51 is a ~79 kDa protein. Specifically deubiquitinates 'Lys-14' (H2AK13Ub) and 'Lys-16'(H2AK15Ub) of histone H2A regulating the DNA damage response at double-strand breaks (DSBs). USP51 is recruited to chromatin after DNA damage and regulates the dynamic assembly/disassembly of TP53BP1 and BRCA1. Functions in DNA double-strand break repair also by mediating the deubiquitination and subsequent stabilization of DGCR8, leading to the recruitment of DGCR8 binding partners to double strand breaks such as RNF168 or MDC1. In addition, promotes the deubiquitination and stabilization of the transcriptional repressor ZEB1. 1. Wang, Z. et al. (2016) Genes & development 30, 946-59. PMID: 27083998 2. Walser, F. et al. (2020) Molecular cell 80, 423-436.e9. PMID: 33022275 3. Hang, Q. et al. (2021) Nature communications 12, 4033. PMID: 34188037 4. Zhou, Z. et al. (2017) American journal of cancer research 7, 2020-2031. PMID: 29119051
Note	For research use only

图片

参考文献

产品说明书

Human USP51 Recombinant Protein (N-His).pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Human USP51 Recombinant Protein (N-His) (HD003012)

概述

图片

参考文献

产品说明书

相关产品推荐

重组蛋白

抗体

试剂盒

实验相关试剂

Human USP51 Recombinant Protein (N-His) (HD003012)

概述

图片

参考文献

产品说明书

相关产品推荐

获取报价