Human SUCNR1 Recombinant Protein (N-His-KSI) (HD131012)

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1mg

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概述

货号	HD131012
品牌	abinScience
描述	Recombinant Human SUCNR1 Protein, N-His-KSI (HD131012) expressed in E. coli. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
表达系统	E. coli
Accession号	Q9BXA5
蛋白长度	Leu2-Gly31&Arg81-His103&Pro159-Leu185&Tyr207-Pro230&Arg252-Arg281&Arg303-Lys334
应用	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
种属	Homo sapiens (Human)
性质	Recombinant
内毒素水平	Please contact with the lab for this information.
纯度	>90% as determined by SDS-PAGE.
预测分子量	35.81 kDa
状态	Lyophilized
保存溶液	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
重悬	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
运输	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名	G-protein coupled receptor 91, GPR91, P2Y purinoceptor 1-like, SUCNR1, Succinate receptor 1
背景	Succinate receptor 1 is a ~38 kDa protein. G protein-coupled receptor for succinate able to mediate signaling through Gq/GNAQ or Gi/GNAI second messengers depending on the cell type and the processes regulated. Succinate-SUCNR1 signaling serves as a link between metabolic stress, inflammation and energy homeostasis. In macrophages, plays a range of immune-regulatory roles. During inflammation, succinate-SUCNR1 signaling may act as an anti-inflammatory mediator or boost inflammation depending on the inflammatory status of cells. Hyperpolarizes M2 macrophages versus M1 phenotype through Gq signaling by regulating the transcription of genes involved in immune function. 1. He, W. et al. (2004) Nature 429, 188-93. PMID: 15141213 2. Sundström, L. et al. (2013) FEBS letters 587, 2399-404. PMID: 23770096 3. Trauelsen, M. et al. (2021) Cell reports 35, 109246. PMID: 34133934 4. Rubic, T. et al. (2008) Nature immunology 9, 1261-9. PMID: 18820681
Note	For research use only

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参考文献

产品说明书

Human SUCNR1 Recombinant Protein (N-His-KSI).pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Human SUCNR1 Recombinant Protein (N-His-KSI) (HD131012)

概述

图片

参考文献

产品说明书

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重组蛋白

抗体

试剂盒

实验相关试剂

Human SUCNR1 Recombinant Protein (N-His-KSI) (HD131012)

概述

图片

参考文献

产品说明书

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