

| 货号 | HD200012 |
|---|---|
| 品牌 | abinScience |
| 描述 |
Recombinant Human SERINC3 Protein, N-His-KSI (HD200012) expressed in E. coli, spanning Gly2-Lys96. Purity: >90% by SDS-PAGE.
Highlights
|
| 表达系统 | E. coli |
| Accession号 | Q13530 |
| 蛋白长度 | Gly2-Lys96 |
| 应用 | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 种属 | Homo sapiens (Human) |
| 性质 | Recombinant |
| 内毒素水平 | Please contact with the lab for this information. |
| 纯度 | >90% as determined by SDS-PAGE. |
| 预测分子量 | 26.11 kDa |
| 状态 | Lyophilized |
| 保存溶液 | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 重悬 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 运输 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 别名 | DIFF33, SERINC3, Serine incorporator 3, TDE1, Tumor differentially expressed protein 1 |
| 背景 | Serine incorporator 3 is a ~52 kDa protein. Restriction factor required to restrict infectivity of lentiviruses, such as HIV-1: acts by inhibiting an early step of viral infection. Impairs the penetration of the viral particle into the cytoplasm. Non-ATP-dependent, non-specific lipid transporter for phosphatidylserine, phosphatidylcholine, and phosphatidylethanolamine. Functions as a scramblase that flips lipids in both directions across the membrane. Phospholipid scrambling results in HIV-1 surface exposure of phosphatidylserine and loss of membrane asymmetry, which leads to changes in HIV-1 Env conformation and loss of infectivity. 1. Usami, Y. et al. (2015) Nature 526, 218-23. PMID: 26416733 2. Rosa, A. et al. (2015) Nature 526, 212-7. PMID: 26416734 3. Leonhardt, SA. et al. (2023) Nature communications 14, 4368. PMID: 37474505 |
| Note | For research use only |

24小时产品查询

扫一扫关注我们

专属渠道经理