Human RNASE6 Recombinant Protein (C-His) (HD339011)
概述
图片
参考文献
产品说明书
概述
货号
HD339011
品牌
abinScience
描述
Recombinant Human RNASE6 Protein, C-His (HD339011) expressed in Yeast Cells, spanning Trp24-Leu150. Purity: >90% by SDS-PAGE.
Highlights
●His-Tagged — N-terminal 6×His tag for IMAC purification.
●High Purity — >90% purity verified by SDS-PAGE.
表达系统
Yeast cells
Accession号
Q93091
蛋白长度
Trp24-Leu150
应用
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
种属
Homo sapiens (Human)
性质
Recombinant
内毒素水平
Please contact with the lab for this information.
纯度
>90% as determined by SDS-PAGE.
预测分子量
15.97 kDa
状态
Lyophilized
保存溶液
Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.
Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
重悬
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
运输
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
稳定性和存储
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Ribonuclease K6 is a ~17 kDa protein. Ribonuclease which shows a preference for the pyrimidines uridine and cytosine. Has potent antibacterial activity against a range of Gram-positive and Gram-negative bacteria, including P.aeruginosa, A.baumanii, M.luteus, S.aureus, E.faecalis, E.faecium, S.saprophyticus and E.coli. Causes loss of bacterial membrane integrity, and also promotes agglutination of Gram-negative bacteria. Probably contributes to urinary tract sterility. Bactericidal activity is independent of RNase activity.
1. Prats-Ejarque, G. et al. (2016) The Biochemical journal 473, 1523-36. PMID: 27013146
2. Rosenberg, HF. et al. (1996) Nucleic acids research 24, 3507-13. PMID: 8836175
3. Becknell, B. et al. (2015) Kidney international 87, 151-61. PMID: 25075772
4. Pulido, D. et al. (2016) International journal of molecular sciences 17, 552. PMID: 27089320
