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Human SLC5A6 Recombinant Protein (N-His-KSI) (HD384012)

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  • 50ug
  • 100ug
  • 1mg
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概述
货号HD384012
品牌abinScience
描述
Recombinant Human SLC5A6 Protein, N-His-KSI (HD384012) expressed in E. coli. Purity: >90% by SDS-PAGE.
Highlights
  • ●His-Tagged — N-terminal 6×His tag for IMAC purification.
  • ●E. coli Expression — High-yield, cost-effective production.
  • ●High Purity — >90% purity verified by SDS-PAGE.
表达系统E. coli
Accession号Q9Y289
蛋白长度Tyr122-Thr140&Asn274-Ser293&Ala317-Pro352&Gly550-Leu636
应用ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
种属Homo sapiens (Human)
性质Recombinant
内毒素水平Please contact with the lab for this information.
纯度>90% as determined by SDS-PAGE.
预测分子量34.35 kDa
状态Lyophilized
保存溶液 Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

重悬Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
运输In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名Na(+)-dependent multivitamin transporter, SLC5A6, SMVT, Sodium-dependent multivitamin transporter, Solute carrier family 5 member 6, hSMVT
背景

Sodium-dependent multivitamin transporter is a ~68 kDa protein. Sodium-dependent multivitamin transporter that mediates the electrogenic transport of pantothenate, biotin, lipoate and iodide. Functions as a Na(+)-coupled substrate symporter where the stoichiometry of Na(+):substrate is 2:1, creating an electrochemical Na(+) gradient used as driving force for substrate uptake. Required for biotin and pantothenate uptake in the intestine across the brush border membrane. Plays a role in the maintenance of intestinal mucosa integrity, by providing the gut mucosa with biotin. Contributes to the luminal uptake of biotin and pantothenate into the brain across the blood-brain barrier.

1. Wang, H. et al. (1999) The Journal of biological chemistry 274, 14875-83. PMID: 10329687
2. Balamurugan, K. et al. (2005) American journal of physiology. Renal physiology 288, F823-31. PMID: 15561972
3. Subramanian, VS. et al. (2009) American journal of physiology. Cell physiology 296, C663-71. PMID: 19211916
4. de Carvalho, FD. et al. (2011) The Journal of biological chemistry 286, 131-7. PMID: 20980265
5. Ghosal, A. et al. (2011) Biochimica et biophysica acta 1808, 2073-80. PMID: 21570947
6. Ghosal, A. et al. (2012) Biochimica et biophysica acta 1818, 97-102. PMID: 22015582
7. Uchida, Y. et al. (2015) Journal of neurochemistry 134, 97-112. PMID: 25809983
8. Zehnpfennig, B. et al. (2015) The Journal of biological chemistry 290, 16372-82. PMID: 25971966
9. Subramanian, VS. et al. (2017) Human genetics 136, 253-261. PMID: 27904971
10. Lakhan, R. et al. (2017) American journal of physiology. Cell physiology 312, C376-C384. PMID: 28052864
NoteFor research use only
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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