ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
种属
Mus musculus (Mouse)
性质
Recombinant
内毒素水平
Please contact with the lab for this information.
纯度
>90% as determined by SDS-PAGE.
预测分子量
32.21 kDa
状态
Lyophilized
保存溶液
Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.
Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
重悬
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
运输
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
稳定性和存储
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名
(3R)-hydroxyacyl-CoA dehydrogenase, 17-beta-HSD 4, 17-beta-hydroxysteroid dehydrogenase 4, 3-alpha,7-alpha,12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA hydratase, D-bifunctional protein, DBP, EC:1.1.1.n12, EC:4.2.1.107, EC:4.2.1.119, EDH17B4, Enoyl-CoA hydratase 2, HSD17B4, MFE-2, MFP-2, Multifunctional protein 2, Peroxisomal multifunctional enzyme type 2, SDR8C1, Short chain dehydrogenase/reductase family 8C member 1
背景
Peroxisomal multifunctional enzyme type 2 is a ~79 kDa protein. Bifunctional enzyme acting on the peroxisomal fatty acid beta-oxidation pathway. Catalyzes two of the four reactions in fatty acid degradation: hydration of 2-enoyl-CoA (trans-2-enoyl-CoA) to produce (3R)-3-hydroxyacyl-CoA, and dehydrogenation of (3R)-3-hydroxyacyl-CoA to produce 3-ketoacyl-CoA (3-oxoacyl-CoA), which is further metabolized by SCPx. Can use straight-chain and branched-chain fatty acids, as well as bile acid intermediates as substrates.
1. Dirkx, R. et al. (2007) Biochemical and biophysical research communications 357, 718-23. PMID: 17442273
