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Mouse DR6/TNFRSF21 Recombinant Protein (C-Fc) (MF685021)

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规格:
  • 50ug
  • 100ug
  • 1mg
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概述
货号MF685021
品牌abinScience
描述
Recombinant Mouse CD358/TNFRSF21 Protein, C-Fc (MF685021) expressed in Mammalian Cells, spanning Gln42-His349. Purity: >90% by SDS-PAGE.
Highlights
  • ●Fc Fusion — Enhanced stability with Protein A/G purification compatibility.
  • ●Mammalian Expression — Proper folding and native glycosylation.
  • ●High Purity — >90% purity verified by SDS-PAGE.
表达系统Mammalian cells
Accession号Q9EPU5
蛋白长度Gln42-His349
应用ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
种属Mus musculus (Mouse)
性质Recombinant
内毒素水平Please contact with the lab for this information.
纯度>90% as determined by SDS-PAGE.
预测分子量61.91 kDa
状态Lyophilized
保存溶液 Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

重悬Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
运输In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名CD358, DR6, Death receptor 6, TNFRSF21, Tumor necrosis factor receptor superfamily member 21
背景

Tumor necrosis factor receptor superfamily member 21 is a ~71 kDa protein. Promotes apoptosis, possibly via a pathway that involves the activation of NF-kappa-B. Can also promote apoptosis mediated by BAX and by the release of cytochrome c from the mitochondria into the cytoplasm. Trophic-factor deprivation triggers the cleavage of surface APP by beta-secretase to release sAPP-beta which is further cleaved to release an N-terminal fragment of APP (N-APP). Negatively regulates oligodendrocyte survival, maturation and myelination. Plays a role in signaling cascades triggered by stimulation of T-cell receptors, in the adaptive immune response and in the regulation of T-cell differentiation and proliferation.

1. Liu, J. et al. (2001) Immunity 15, 23-34. PMID: 11485735
2. Zhao, H. et al. (2001) The Journal of experimental medicine 194, 1441-8. PMID: 11714751
3. Schmidt, CS. et al. (2003) The Journal of experimental medicine 197, 51-62. PMID: 12515813
4. Mi, S. et al. (2011) Nature medicine 17, 816-21. PMID: 21725297
5. Hu, Y. et al. (2013) Cell death & disease 4, e579. PMID: 23559013
NoteFor research use only
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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