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Mouse TNFSF18/GITRL Recombinant Protein (C-Fc) (MP087021)

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  • 100ug
  • 1mg
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概述
货号MP087021
品牌abinScience
描述
Recombinant Mouse TNFSF18/GITRL Protein, C-Fc (MP087021) expressed in Mammalian Cells, spanning Thr47-Ser173. Purity: >90% by SDS-PAGE.
Highlights
  • Fc Fusion — Enhanced stability with Protein A/G purification compatibility.
  • Mammalian Expression — Proper folding and native glycosylation.
  • High Purity — >90% purity verified by SDS-PAGE.
表达系统Mammalian cells
Accession号Q7TS55
蛋白长度Thr47-Ser173
应用ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
种属Mus musculus (Mouse)
性质Recombinant
内毒素水平Please contact with the lab for this information.
纯度>90% as determined by SDS-PAGE.
预测分子量42.82 kDa
状态Lyophilized
保存溶液 Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

重悬Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
运输In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名AITRL, Activation-inducible TNF-related ligand, GITRL, Glucocorticoid-induced TNF-related ligand, TL6, TNFSF18, Tumor necrosis factor ligand superfamily member 18, hGITRL
背景

Tumor necrosis factor ligand superfamily member 18 is a ~19 kDa protein. Cytokine that binds to TNFRSF18/AITR/GITR. Regulates T-cell responses. Can function as costimulator and lower the threshold for T-cell activation and T-cell proliferation. Important for interactions between activated T-lymphocytes and endothelial cells. Mediates activation of NF-kappa-B.

1. Yu, KY. et al. (2003) Biochemical and biophysical research communications 310, 433-8. PMID: 14521928
2. Kim, JD. et al. (2003) Genes and immunity 4, 564-9. PMID: 14647196
3. Tone, M. et al. (2003) Proceedings of the National Academy of Sciences of the United States of America 100, 15059-64. PMID: 14608036
4. Ji, HB. et al. (2004) Journal of immunology (Baltimore, Md. : 1950) 172, 5823-7. PMID: 15128759
5. Zhou, Z. et al. (2008) Proceedings of the National Academy of Sciences of the United States of America 105, 641-5. PMID: 18178614
6. Lacal, PM. et al. (2013) The Journal of pharmacology and experimental therapeutics 347, 164-72. PMID: 23892569
7. Liao, G. et al. (2014) FASEB journal : official publication of the Federation of American Societies for Experimental Biology 28, 474-84. PMID: 24107315
NoteFor research use only
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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