ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
种属
Homo sapiens (Human)
性质
Recombinant
内毒素水平
Please contact with the lab for this information.
纯度
>90% as determined by SDS-PAGE.
预测分子量
23.99 kDa
状态
Lyophilized
保存溶液
Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.
Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
重悬
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
运输
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
稳定性和存储
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名
CENP-J, CENPJ, CPAP, Centromere protein J, Centrosomal P4.1-associated protein, Centrosome assembly and centriole elongation protein, LAG-3-associated protein, LAP, LIP1, LYST-interacting protein 1
背景
Centrosomal P4.1-associated protein is a ~153 kDa protein. Plays an important role in cell division and centrosome function by participating in centriole duplication. Inhibits microtubule nucleation from the centrosome. Involved in the regulation of slow processive growth of centriolar microtubules. Acts as a microtubule plus-end tracking protein that stabilizes centriolar microtubules and inhibits microtubule polymerization and extension from the distal ends of centrioles. Required for centriole elongation and for STIL-mediated centriole amplification.
1. Kleylein-Sohn, J. et al. (2007) Developmental cell 13, 190-202. PMID: 17681131
2. Chang, J. et al. (2010) The EMBO journal 29, 2395-406. PMID: 20531387
3. Hung, LY. et al. (2004) Molecular biology of the cell 15, 2697-706. PMID: 15047868
4. Sharma, A. et al. (2016) Developmental cell 37, 362-376. PMID: 27219064
