ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
种属
Homo sapiens (Human)
性质
Recombinant
内毒素水平
Please contact with the lab for this information.
纯度
>90% as determined by SDS-PAGE.
预测分子量
16.26 kDa
状态
Lyophilized
保存溶液
Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.
Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
重悬
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
运输
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
稳定性和存储
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名
BDGI, BMSC-derived growth inhibitor, Bone marrow stromal cell-derived growth inhibitor, EC:1.14.13.-, OKL38, OSGIN1, Ovary, kidney and liver protein 38, Oxidative stress-induced growth inhibitor 1, Pregnancy-induced growth inhibitor OKL38, huOKL38
背景
Oxidative stress-induced growth inhibitor 1 is a ~51 kDa protein. Monooxygenase catalytic activity. Involved in regulation of cytokinesis; promotes RHOA activity, probably acting locally at the midbody in late cytokinesis. Monooxygenase activity is involved in stabilizing transient structures between daughter cells, termed intercellular bridges, before abscission. Regulates differentiation and proliferation through the regulation of cell death.
1. Goupil, E. et al. (2024) Proceedings of the National Academy of Sciences of the United States of America 121, e2308570121. PMID: 38442170
2. Huynh, H. et al. (2001) Endocrinology 142, 3607-15. PMID: 11459809
3. Ong, CK. et al. (2004) The Journal of biological chemistry 279, 743-54. PMID: 14570898
