

| 货号 | HP433011 |
|---|---|
| 品牌 | abinScience |
| 描述 |
Recombinant Human ARTN/Artemin Protein, N-Fc (HP433011) expressed in Mammalian Cells, spanning Ala108-Gly220. Purity: >90% by SDS-PAGE.
Highlights
|
| 表达系统 | Mammalian cells |
| Accession号 | Q5T4W7 |
| 蛋白长度 | Ala108-Gly220 |
| 应用 | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 种属 | Homo sapiens (Human) |
| 性质 | Recombinant |
| 内毒素水平 | Please contact with the lab for this information. |
| 纯度 | >90% as determined by SDS-PAGE. |
| 预测分子量 | 39.80 kDa |
| 状态 | Lyophilized |
| 保存溶液 | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 重悬 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 运输 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 别名 | ARTN, Artemin, EVN, Enovin, Neublastin |
| 背景 | Artemin is a ~22 kDa protein. Growth factor that supports the survival of sensory and sympathetic peripheral neurons in culture and also supports the survival of dopaminergic neurons of the ventral mid-brain. Acts by binding to its coreceptor, GFRA3, leading to autophosphorylation and activation of the RET receptor. Strong attractant of gut hematopoietic cells thus promoting the formation Peyer's patch-like structures, a major component of the gut-associated lymphoid tissue. 1. Masure, S. et al. (1999) European journal of biochemistry 266, 892-902. PMID: 10583383 2. Baloh, RH. et al. (1998) Neuron 21, 1291-302. PMID: 9883723 3. Li, J. et al. (2019) eLife 8. PMID: 31535977 |
| Note | For research use only |

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