Mouse VISTA/B7-H5/PD-1H Recombinant Protein (C-Fc) (MP543021)
概述
图片
参考文献
产品说明书
概述
货号
MP543021
品牌
abinScience
描述
Recombinant Mouse VSIR/VISTA Protein, C-Fc (MP543021) expressed in Mammalian Cells, spanning Phe33-Ala191. Purity: >90% by SDS-PAGE.
Highlights
●Fc Fusion — Enhanced stability with Protein A/G purification compatibility.
●Mammalian Expression — Proper folding and native glycosylation.
●High Purity — >90% purity verified by SDS-PAGE.
表达系统
Mammalian cells
Accession号
Q9D659
蛋白长度
Phe33-Ala191
应用
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
种属
Mus musculus (Mouse)
性质
Recombinant
内毒素水平
Please contact with the lab for this information.
纯度
>90% as determined by SDS-PAGE.
预测分子量
46.10 kDa
状态
Lyophilized
保存溶液
Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.
Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
重悬
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
运输
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
稳定性和存储
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
V-type immunoglobulin domain-containing suppressor of T-cell activation is a ~33 kDa protein. Immunoregulatory receptor which inhibits the T-cell response. May promote differentiation of embryonic stem cells, by inhibiting BMP4 signaling. May stimulate MMP14-mediated MMP2 activation.
1. Wang, L. et al. (2011) The Journal of experimental medicine 208, 577-92. PMID: 21383057
2. Flies, DB. et al. (2014) The Journal of clinical investigation 124, 1966-75. PMID: 24743150
3. Wang, L. et al. (2014) Proceedings of the National Academy of Sciences of the United States of America 111, 14846-51. PMID: 25267631
4. Aloia, L. et al. (2010) The Journal of biological chemistry 285, 7776-83. PMID: 20042595
