Human RICTOR Recombinant Protein (N-His) (HP601022)

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概述

货号	HP601022
品牌	abinScience
描述	Recombinant Human RICTOR Protein, N-His (HP601022) expressed in E. coli, spanning Arg32-Leu254. Purity: >90% by SDS-PAGE. Highlights ●His-Tagged — N-terminal 6×His tag for IMAC purification. ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% purity verified by SDS-PAGE.
表达系统	E. coli
Accession号	Q6R327
蛋白长度	Arg32-Leu254
应用	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
种属	Homo sapiens (Human)
性质	Recombinant
内毒素水平	Please contact with the lab for this information.
纯度	>90% as determined by SDS-PAGE.
预测分子量	27.56 kDa
状态	Lyophilized
保存溶液	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
重悬	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
运输	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名	AVO3 homolog, KIAA1999, RICTOR, Rapamycin-insensitive companion of mTOR, hAVO3
背景	Rapamycin-insensitive companion of mTOR is a ~192 kDa protein. Component of the mechanistic target of rapamycin complex 2 (mTORC2), which transduces signals from growth factors to pathways involved in proliferation, cytoskeletal organization, lipogenesis and anabolic output. In response to growth factors, mTORC2 phosphorylates and activates AGC protein kinase family members, including AKT (AKT1, AKT2 and AKT3), PKC (PRKCA, PRKCB and PRKCE) and SGK1. In contrast to mTORC1, mTORC2 is nutrient-insensitive. Within the mTORC2 complex, RICTOR probably acts as a molecular adapter. RICTOR is responsible for the FKBP12-rapamycin-insensitivity of mTORC2. 1. Sarbassov, DD. et al. (2004) Current biology : CB 14, 1296-302. PMID: 15268862 2. Sarbassov, DD. et al. (2005) Science (New York, N.Y.) 307, 1098-101. PMID: 15718470 3. Dibble, CC. et al. (2009) Molecular and cellular biology 29, 5657-70. PMID: 19720745 4. Julien, LA. et al. (2010) Molecular and cellular biology 30, 908-21. PMID: 19995915 5. Chen, CH. et al. (2011) Science signaling 4, ra10. PMID: 21343617 6. Scaiola, A. et al. (2020) Science advances 6. PMID: 33158864 7. Zhuang, L. et al. (2022) Cell biology international 46, 1693-1703. PMID: 35904232 8. Yu, Z. et al. (2022) The Journal of biological chemistry 298, 102288. PMID: 35926713 9. Treins, C. et al. (2010) Oncogene 29, 1003-16. PMID: 19935711 10. Jacinto, E. et al. (2004) Nature cell biology 6, 1122-8. PMID: 15467718
Note	For research use only

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参考文献

产品说明书

Human RICTOR Recombinant Protein (N-His).pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

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Human RICTOR Recombinant Protein (N-His) (HP601022)

概述

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参考文献

产品说明书

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重组蛋白

抗体

试剂盒

实验相关试剂

Human RICTOR Recombinant Protein (N-His) (HP601022)

概述

图片

参考文献

产品说明书

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