

| 货号 | HT100011 |
|---|---|
| 品牌 | abinScience |
| 描述 |
Recombinant Human AGRP Protein, C-Fc (HT100011) expressed in Mammalian Cells, spanning Met1-Thr132. Purity: >90% by SDS-PAGE.
Highlights
|
| 表达系统 | Mammalian cells |
| Accession号 | O00253 |
| 蛋白长度 | Met1-Thr132 |
| 应用 | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 种属 | Homo sapiens (Human) |
| 性质 | Recombinant |
| 内毒素水平 | Please contact with the lab for this information. |
| 纯度 | >90% as determined by SDS-PAGE. |
| 预测分子量 | 40.84 kDa |
| 状态 | Lyophilized |
| 保存溶液 | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 重悬 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 运输 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 别名 | AGRP, AGRT, ART, Agouti-related protein |
| 背景 | Agouti-related protein is a ~14 kDa protein. Signaling protein that functions as an antagonist of melanocyte-stimulating-hormone receptors MC3R and MC4R by precluding agonist-induced signaling, thereby inhibiting cAMP production within the hypothalamus and adrenal gland. Involved in the control of feeding behavior via the central melanocortin system. Has very low activity towards MC5R. Also promotes endocytosis of MC3R and MC4R in an arrestin-dependent mechanism. 1. Bolin, KA. et al. (1999) FEBS letters 451, 125-31. PMID: 10371151 2. Nijenhuis, WA. et al. (2001) Molecular endocrinology (Baltimore, Md.) 15, 164-71. PMID: 11145747 3. Ollmann, MM. et al. (1997) Science (New York, N.Y.) 278, 135-8. PMID: 9311920 4. Yang, YK. et al. (1999) Molecular endocrinology (Baltimore, Md.) 13, 148-55. PMID: 9892020 5. de Rijke, CE. et al. (2005) Biochemical pharmacology 70, 308-16. PMID: 15927146 6. Breit, A. et al. (2006) The Journal of biological chemistry 281, 37447-56. PMID: 17041250 |
| Note | For research use only |

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