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Human AGRP Recombinant Protein (C-Fc) (HT100011)

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规格:
  • 50ug
  • 100ug
  • 1mg
数量:
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概述
货号HT100011
品牌abinScience
描述
Recombinant Human AGRP Protein, C-Fc (HT100011) expressed in Mammalian Cells, spanning Met1-Thr132. Purity: >90% by SDS-PAGE.
Highlights
  • ●Fc Fusion — Enhanced stability with Protein A/G purification compatibility.
  • ●Mammalian Expression — Proper folding and native glycosylation.
  • ●High Purity — >90% purity verified by SDS-PAGE.
表达系统Mammalian cells
Accession号O00253
蛋白长度Met1-Thr132
应用ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
种属Homo sapiens (Human)
性质Recombinant
内毒素水平Please contact with the lab for this information.
纯度>90% as determined by SDS-PAGE.
预测分子量40.84 kDa
状态Lyophilized
保存溶液 Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

重悬Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
运输In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名AGRP, AGRT, ART, Agouti-related protein
背景

Agouti-related protein is a ~14 kDa protein. Signaling protein that functions as an antagonist of melanocyte-stimulating-hormone receptors MC3R and MC4R by precluding agonist-induced signaling, thereby inhibiting cAMP production within the hypothalamus and adrenal gland. Involved in the control of feeding behavior via the central melanocortin system. Has very low activity towards MC5R. Also promotes endocytosis of MC3R and MC4R in an arrestin-dependent mechanism.

1. Bolin, KA. et al. (1999) FEBS letters 451, 125-31. PMID: 10371151
2. Nijenhuis, WA. et al. (2001) Molecular endocrinology (Baltimore, Md.) 15, 164-71. PMID: 11145747
3. Ollmann, MM. et al. (1997) Science (New York, N.Y.) 278, 135-8. PMID: 9311920
4. Yang, YK. et al. (1999) Molecular endocrinology (Baltimore, Md.) 13, 148-55. PMID: 9892020
5. de Rijke, CE. et al. (2005) Biochemical pharmacology 70, 308-16. PMID: 15927146
6. Breit, A. et al. (2006) The Journal of biological chemistry 281, 37447-56. PMID: 17041250
NoteFor research use only
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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