

| 货号 | HV262011 |
|---|---|
| 品牌 | abinScience |
| 描述 |
Recombinant Human RNASE7 Protein, C-His (HV262011) expressed in Yeast Cells, spanning Lys29-Leu156. Purity: >90% by SDS-PAGE.
Highlights
|
| 表达系统 | Yeast cells |
| Accession号 | Q9H1E1 |
| 蛋白长度 | Lys29-Leu156 |
| 应用 | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 种属 | Homo sapiens (Human) |
| 性质 | Recombinant |
| 内毒素水平 | Please contact with the lab for this information. |
| 纯度 | >90% as determined by SDS-PAGE. |
| 预测分子量 | 15.82 kDa |
| 状态 | Lyophilized |
| 保存溶液 | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 重悬 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 运输 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 别名 | EC:3.1.27.-, RNASE7, RNase 7, Ribonuclease 7, SAP-2, Skin-derived antimicrobial protein 2 |
| 背景 | Ribonuclease 7 is a ~17 kDa protein. Exhibits a potent RNase activity. Has broad-spectrum antimicrobial activity against many pathogenic microorganisms including uropathogenic E.coli (UPEC), and remarkably potent activity (lethal dose of 90% < 30 nM) against a vancomycin resistant Enterococcus faecium. Causes loss of bacterial membrane integrity. Probably contributes to urinary tract sterility. Bactericidal activity is independent of RNase activity. 1. Harder, J. et al. (2002) The Journal of biological chemistry 277, 46779-84. PMID: 12244054 2. Zhang, J. et al. (2003) Nucleic acids research 31, 602-7. PMID: 12527768 3. Huang, YC. et al. (2007) The Journal of biological chemistry 282, 4626-4633. PMID: 17150966 4. Becknell, B. et al. (2015) Kidney international 87, 151-61. PMID: 25075772 5. Bender, K. et al. (2021) American journal of physiology. Renal physiology 320, F972-F983. PMID: 33818125 |
| Note | For research use only |

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