Human CD273/PD-L2/PDCD1LG2 Recombinant Protein (C-Fc) (HV809021)
概述
图片
参考文献
产品说明书
概述
货号
HV809021
品牌
abinScience
描述
Recombinant Human CD273/PD-L2/PDCD1LG2 Protein, C-Fc (HV809021) expressed in Mammalian Cells, spanning Met1-Thr220. Purity: >90% by SDS-PAGE.
Highlights
●Fc Fusion — Enhanced stability with Protein A/G purification compatibility.
●Mammalian Expression — Proper folding and native glycosylation.
●High Purity — >90% purity verified by SDS-PAGE.
表达系统
Mammalian cells
Accession号
Q9BQ51
蛋白长度
Met1-Thr220
应用
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
种属
Homo sapiens (Human)
性质
Recombinant
内毒素水平
Please contact with the lab for this information.
纯度
>90% as determined by SDS-PAGE.
预测分子量
51.24 kDa
状态
Lyophilized
保存溶液
Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.
Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
重悬
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
运输
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
稳定性和存储
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Programmed cell death 1 ligand 2 is a ~30 kDa protein. Plays a critical role in induction and maintenance of immune tolerance to self. Acts as a ligand for the inhibitory receptor PDCD1/PD-1, inhibiting T-cell proliferation by blocking cell cycle progression and cytokine production.
1. Latchman, Y. et al. (2001) Nature immunology 2, 261-8. PMID: 11224527
2. Brown, JA. et al. (2003) Journal of immunology (Baltimore, Md. : 1950) 170, 1257-66. PMID: 12538684
Note
For research use only
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Bioactivity
Immobilized HS870031 Human PD-1 Recombinant Protein (C-Fc) at 2 μg/mL(100 μL/well) can bind HV809021 Human CD273/PD-L2/PDCD1LG2 Recombinant Protein (C-Fc), the EC 50 is 324 ng/mL.
