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Human KCNJ2/Kir2.1 Recombinant Protein (N-His) (HX945012)

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规格:
  • 50ug
  • 100ug
  • 1mg
数量:
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概述
货号HX945012
品牌abinScience
描述
Recombinant Human KCNJ2/Kir2.1 Protein, N-His (HX945012) expressed in E. coli, spanning Lys185-Glu349. Purity: >90% by SDS-PAGE.
Highlights
  • ●His-Tagged — N-terminal 6×His tag for IMAC purification.
  • ●E. coli Expression — High-yield, cost-effective production.
  • ●High Purity — >90% purity verified by SDS-PAGE.
表达系统E. coli
Accession号P63252
蛋白长度Lys185-Glu349
应用ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
种属Homo sapiens (Human)
性质Recombinant
内毒素水平Please contact with the lab for this information.
纯度>90% as determined by SDS-PAGE.
预测分子量21.48 kDa
状态Lyophilized
保存溶液 Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

重悬Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
运输In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名Cardiac inward rectifier potassium channel, IRK-1, IRK1, Inward rectifier K(+) channel Kir2.1, Inward rectifier potassium channel 2, KCNJ2, Potassium channel, inwardly rectifying subfamily J member 2, hIRK1
背景

Inward rectifier potassium channel 2 is a ~48 kDa protein. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium or cesium. Probably participates in establishing action potential waveform and excitability of neuronal and muscle tissues.

1. Fernandes, CAH. et al. (2022) Science advances 8, eabq8489. PMID: 36149965
2. Wood, LS. et al. (1995) Gene 163, 313-7. PMID: 7590287
3. Tare, M. et al. (1998) The Journal of physiology 506 ( Pt 2), 303-18. PMID: 9490857
4. Raab-Graham, KF. et al. (1994) Neuroreport 5, 2501-5. PMID: 7696590
NoteFor research use only
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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