ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
种属
Homo sapiens (Human)
性质
Recombinant
内毒素水平
Please contact with the lab for this information.
纯度
>90% as determined by SDS-PAGE.
预测分子量
41.71 kDa
状态
Lyophilized
保存溶液
Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.
Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
重悬
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
运输
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
稳定性和存储
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Serine protease hepsin is a ~45 kDa protein. Serine protease that cleaves extracellular substrates, and contributes to the proteolytic processing of growth factors, such as HGF and MST1/HGFL. Plays a role in cell growth and maintenance of cell morphology. Plays a role in the proteolytic processing of ACE2. Mediates the proteolytic cleavage of urinary UMOD that is required for UMOD polymerization.
1. Herter, S. et al. (2005) The Biochemical journal 390, 125-36. PMID: 15839837
2. Ganesan, R. et al. (2011) Molecular cancer research : MCR 9, 1175-86. PMID: 21875933
3. Torres-Rosado, A. et al. (1993) Proceedings of the National Academy of Sciences of the United States of America 90, 7181-5. PMID: 8346233
4. Heurich, A. et al. (2014) Journal of virology 88, 1293-307. PMID: 24227843
5. Brunati, M. et al. (2015) eLife 4, e08887. PMID: 26673890
