

| 货号 | MY262012 |
|---|---|
| 品牌 | abinScience |
| 描述 |
Recombinant Mouse IL3 Protein, N-His (MY262012) expressed in E. coli, spanning Asp33-Cys166. Purity: >90% by SDS-PAGE.
Highlights
|
| 表达系统 | E. coli |
| Accession号 | P01586 |
| 蛋白长度 | Asp33-Cys166 |
| 应用 | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 种属 | Mus musculus (Mouse) |
| 性质 | Recombinant |
| 内毒素水平 | Please contact with the lab for this information. |
| 纯度 | >90% as determined by SDS-PAGE. |
| 预测分子量 | 17.40 kDa |
| 状态 | Lyophilized |
| 保存溶液 | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 重悬 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 运输 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 别名 | Hematopoietic growth factor, IL-3, IL3, Interleukin-3, MCGF, Mast cell growth factor, Multipotential colony-stimulating factor, P-cell-stimulating factor |
| 背景 | Interleukin-3 is a ~18 kDa protein. Cytokine secreted predominantly by activated T-lymphocytes as well as mast cells and osteoblastic cells that controls the production and differentiation of hematopoietic progenitor cells into lineage-restricted cells. Also stimulates mature basophils, eosinophils, and monocytes to become functionally activated. In addition, plays an important role in neural cell proliferation and survival. Participates as well in bone homeostasis and inhibits osteoclast differentiation by preventing NF-kappa-B nuclear translocation and activation. Mechanistically, exerts its biological effects through a receptor composed of IL3RA subunit and a signal transducing subunit IL3RB. 1. Jaster, R. et al. (1999) Cellular signalling 11, 331-5. PMID: 10376805 2. Tong, Y. et al. (2020) JCI insight 5. PMID: 31990690 3. Silvennoinen, O. et al. (1993) Proceedings of the National Academy of Sciences of the United States of America 90, 8429-33. PMID: 8378315 |
| Note | For research use only |

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