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HTNV Glycoprotein Gn Recombinant Protein (C-His) (VK646061)

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规格:
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  • 100ug
  • 1mg
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概述
货号VK646061
品牌abinScience
描述
Recombinant HTNV/KHFV Glycoprotein N/Gn/G1, C-His (VK646061) expressed in Mammalian Cells. Purity: >90% as determined by SDS-PAGE..
Highlights
  • High Purity — >90% as determined by SDS-PAGE.
表达系统Mammalian cells
Accession号P08668
蛋白长度Leu19-Glu371
应用ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
种属Korean hemorrhagic fever virus (KHFV) (Hantaan virus) (HTNV)
性质Recombinant
内毒素水平Please contact with the lab for this information.
纯度>90% as determined by SDS-PAGE.
状态Lyophilized
保存溶液 Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

重悬Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
运输In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名Envelopment polyprotein, GP, Gc, Glycoprotein C, Glycoprotein G1, Glycoprotein G2, Glycoprotein N, Glycoprotein precursor, Gn, M polyprotein
背景

Envelopment polyprotein is a ~126 kDa protein. Forms homotetramers with glycoprotein C at the surface of the virion. Attaches the virion to host cell receptors including integrin ITGAV/ITGB3. This attachment induces virion internalization predominantly through clathrin-dependent endocytosis. May also bind to host C1QBP for virus entry into the host cell. Mediates the assembly and budding of infectious virus particles through its interaction with the nucleocapsid protein and the viral genome.

1. Raymond, T. et al. (2005) Proceedings of the National Academy of Sciences of the United States of America 102, 1163-8. PMID: 15657120
2. Mou, DL. et al. (2006) Biochemical and biophysical research communications 339, 611-7. PMID: 16310165
3. Müller, A. et al. (2019) Virus research 267, 36-40. PMID: 31054291
4. Jin, M. et al. (2002) Virology 294, 60-9. PMID: 11886265
5. Choi, Y. et al. (2008) Virology 381, 178-83. PMID: 18834607
6. Wang, K. et al. (2019) Cell reports 27, 2075-2091.e5. PMID: 31091447
NoteFor research use only
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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