HTNV Glycoprotein Gn Recombinant Protein (C-Fc) (VK646071)
概述
图片
参考文献
产品说明书
概述
货号
VK646071
品牌
abinScience
描述
Recombinant HTNV/KHFV Glycoprotein N/Gn/G1, C-Fc (VK646071) expressed in Mammalian Cells. Purity: >90% as determined by SDS-PAGE..
Highlights
●High Purity — >90% as determined by SDS-PAGE.
表达系统
Mammalian cells
Accession号
P08668
蛋白长度
Leu19-Glu371
应用
ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
种属
Korean hemorrhagic fever virus (KHFV) (Hantaan virus) (HTNV)
性质
Recombinant
内毒素水平
Please contact with the lab for this information.
纯度
>90% as determined by SDS-PAGE.
状态
Lyophilized
保存溶液
Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.
Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
重悬
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
运输
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
稳定性和存储
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名
Envelopment polyprotein, GP, Gc, Glycoprotein C, Glycoprotein G1, Glycoprotein G2, Glycoprotein N, Glycoprotein precursor, Gn, M polyprotein
背景
Envelopment polyprotein is a ~126 kDa protein. Forms homotetramers with glycoprotein C at the surface of the virion. Attaches the virion to host cell receptors including integrin ITGAV/ITGB3. This attachment induces virion internalization predominantly through clathrin-dependent endocytosis. May also bind to host C1QBP for virus entry into the host cell. Mediates the assembly and budding of infectious virus particles through its interaction with the nucleocapsid protein and the viral genome.
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2. Mou, DL. et al. (2006) Biochemical and biophysical research communications 339, 611-7. PMID: 16310165
3. Müller, A. et al. (2019) Virus research 267, 36-40. PMID: 31054291
4. Jin, M. et al. (2002) Virology 294, 60-9. PMID: 11886265
5. Choi, Y. et al. (2008) Virology 381, 178-83. PMID: 18834607
6. Wang, K. et al. (2019) Cell reports 27, 2075-2091.e5. PMID: 31091447
