

| 货号 | SV999011 |
|---|---|
| 品牌 | abinScience |
| 描述 |
Recombinant Pig IL22 Protein, C-His (SV999011) expressed in Mammalian Cells. Purity: >90% as determined by SDS-PAGE..
Highlights
|
| 表达系统 | Mammalian cells |
| Accession号 | F1SH68 |
| 蛋白长度 | Ala33-Asn190 |
| 应用 | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 种属 | Sus scrofa (Pig) |
| 性质 | Recombinant |
| 内毒素水平 | Please contact with the lab for this information. |
| 纯度 | >90% as determined by SDS-PAGE. |
| 预测分子量 | 21.05 kDa |
| 状态 | Lyophilized |
| 保存溶液 | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 重悬 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 运输 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 别名 | IL22, Interleukin 22 |
| 背景 | Interleukin-22 (Interleukin-22,Cytokine Zcyto18,IL-22,ZCYTO18,IL22,ILTIF,IL-TIF,IL-10-related T-cell-derived-inducible factor) is a ~20 kDa protein. Cytokine that plays a critical role in modulating tissue responses during inflammation. Plays an essential role in the regeneration of epithelial cells to maintain barrier function after injury and for the prevention of further tissue damage. Unlike most of the cytokines, has no effect on immune cells. Signals through a heterodimeric receptor composed of two subunits, the specific receptor IL22RA1 which is present on non-immune cells in many organs and the shared subunit IL10RB. Ligation of IL22RA1 with IL22 induces activation of the tyrosine kinases JAK1 and TYK2, which in turn activates STAT3. 1. Brand, S. et al. (2007) American journal of physiology. Gastrointestinal and liver physiology 292, G1019-28. PMID: 17204547 2. Xie, MH. et al. (2000) The Journal of biological chemistry 275, 31335-9. PMID: 10875937 3. Jones, BC. et al. (2008) Structure (London, England : 1993) 16, 1333-44. PMID: 18599299 4. Akil, H. et al. (2015) PloS one 10, e0119872. PMID: 25793261 5. Moniruzzaman, M. et al. (2019) International journal of molecular sciences 20. PMID: 31311100 |
| Note | For research use only |

24小时产品查询

扫一扫关注我们

专属渠道经理