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Porcine IL-22 Recombinant Protein (C-His) (SV999011)

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规格:
  • 50ug
  • 100ug
  • 1mg
数量:
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概述
货号SV999011
品牌abinScience
描述
Recombinant Pig IL22 Protein, C-His (SV999011) expressed in Mammalian Cells. Purity: >90% as determined by SDS-PAGE..
Highlights
  • ●High Purity — >90% as determined by SDS-PAGE.
表达系统Mammalian cells
Accession号F1SH68
蛋白长度Ala33-Asn190
应用ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
种属Sus scrofa (Pig)
性质Recombinant
内毒素水平Please contact with the lab for this information.
纯度>90% as determined by SDS-PAGE.
预测分子量21.05 kDa
状态Lyophilized
保存溶液 Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

重悬Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
运输In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名IL22, Interleukin 22
背景

Interleukin-22 (Interleukin-22,Cytokine Zcyto18,IL-22,ZCYTO18,IL22,ILTIF,IL-TIF,IL-10-related T-cell-derived-inducible factor) is a ~20 kDa protein. Cytokine that plays a critical role in modulating tissue responses during inflammation. Plays an essential role in the regeneration of epithelial cells to maintain barrier function after injury and for the prevention of further tissue damage. Unlike most of the cytokines, has no effect on immune cells. Signals through a heterodimeric receptor composed of two subunits, the specific receptor IL22RA1 which is present on non-immune cells in many organs and the shared subunit IL10RB. Ligation of IL22RA1 with IL22 induces activation of the tyrosine kinases JAK1 and TYK2, which in turn activates STAT3.

1. Brand, S. et al. (2007) American journal of physiology. Gastrointestinal and liver physiology 292, G1019-28. PMID: 17204547
2. Xie, MH. et al. (2000) The Journal of biological chemistry 275, 31335-9. PMID: 10875937
3. Jones, BC. et al. (2008) Structure (London, England : 1993) 16, 1333-44. PMID: 18599299
4. Akil, H. et al. (2015) PloS one 10, e0119872. PMID: 25793261
5. Moniruzzaman, M. et al. (2019) International journal of molecular sciences 20. PMID: 31311100
NoteFor research use only
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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