

| 货号 | HD643012 |
|---|---|
| 品牌 | abinScience |
| 描述 |
Recombinant Human GFM2 Protein, N-His (HD643012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE..
Highlights
|
| 表达系统 | E. coli |
| Accession号 | Q969S9 |
| 蛋白长度 | Ala461-Thr779 |
| 应用 | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 种属 | Homo sapiens (Human) |
| 性质 | Recombinant |
| 内毒素水平 | Please contact with the lab for this information. |
| 纯度 | >90% as determined by SDS-PAGE. |
| 状态 | Lyophilized |
| 保存溶液 | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 重悬 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 运输 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 别名 | EC:3.6.5.-, EF-G2mt, EFG2, Elongation factor G 2, mitochondrial, Elongation factor G2, GFM2, RRF2mt, Ribosome-releasing factor 2, mitochondrial, hEFG2, mEF-G 2 |
| 背景 | Ribosome-releasing factor 2, mitochondrial is a ~86 kDa protein. Mitochondrial GTPase that mediates the disassembly of ribosomes from messenger RNA at the termination of mitochondrial protein biosynthesis. Acts in collaboration with MRRF. Promotes mitochondrial ribosome recycling by dissolution of intersubunit contacts. GTP hydrolysis follows the ribosome disassembly and probably occurs on the ribosome large subunit. Not involved in the GTP-dependent ribosomal translocation step during translation elongation. 1. Tsuboi, M. et al. (2009) Molecular cell 35, 502-10. PMID: 19716793 2. Kummer, E. et al. (2021) Molecular cell 81, 2566-2582.e6. PMID: 33878294 |
| Note | For research use only |

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