ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
种属
Homo sapiens (Human)
性质
Recombinant
内毒素水平
Please contact with the lab for this information.
纯度
>90% as determined by SDS-PAGE.
状态
Lyophilized
保存溶液
Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.
Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
重悬
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
运输
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
稳定性和存储
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名
ADP-ribosylation factor-like protein 1, ARL1
背景
ADP-ribosylation factor-like protein 1 is a ~20 kDa protein. GTP-binding protein that recruits several effectors, such as golgins, arfaptins and Arf-GEFs to the trans-Golgi network, and modulates their functions at the Golgi complex. Plays thereby a role in a wide range of fundamental cellular processes, including cell polarity, innate immunity, or protein secretion mediated by arfaptins, which were shown to play a role in maintaining insulin secretion from pancreatic beta cells.
1. Man, Z. et al. (2011) The Journal of biological chemistry 286, 11569-78. PMID: 21239483
2. Nakamura, K. et al. (2012) The Journal of biological chemistry 287, 25478-89. PMID: 22679020
3. Galindo, A. et al. (2016) Cell reports 16, 839-50. PMID: 27373159
4. Wang, R. et al. (2016) Journal of molecular cell biology 8, 459-461. PMID: 27436755
5. Hong, JX. et al. (1998) The Journal of biological chemistry 273, 15872-6. PMID: 9624189
6. Lu, L. et al. (2003) Molecular biology of the cell 14, 3767-81. PMID: 12972563
7. Gehart, H. et al. (2012) Developmental cell 23, 756-68. PMID: 22981988
