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Mouse IL-13 Recombinant Protein (N-His) (MW632012)

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规格:
  • 50ug
  • 100ug
  • 1mg
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概述
货号MW632012
品牌abinScience
描述
Recombinant Mouse IL13 Protein, N-His (MW632012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE..
Highlights
  • E. coli Expression — High-yield, cost-effective production.
  • High Purity — >90% as determined by SDS-PAGE.
表达系统E. coli
Accession号P20109
蛋白长度Ser26-Phe131
应用ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
种属Mus musculus (Mouse)
性质Recombinant
内毒素水平Please contact with the lab for this information.
纯度>90% as determined by SDS-PAGE.
状态Lyophilized
保存溶液 Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

重悬Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
运输In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名IL-13, Il-13, Il13, Interleukin-13, T-cell activation protein P600
背景

Interleukin-13 is a ~14 kDa protein. Cytokine that plays important roles in allergic inflammation and immune response to parasite infection. Synergizes with IL2 in regulating interferon-gamma synthesis. Stimulates B-cell proliferation, and activation of eosinophils, basophils, and mast cells. Plays an important role in controlling IL33 activity by modulating the production of transmembrane and soluble forms of interleukin-1 receptor-like 1/IL1RL1. Displays the capacity to antagonize Th1-driven proinflammatory immune response and downregulates synthesis of many proinflammatory cytokines including IL1, IL6, IL10, IL12 and TNF through a mechanism that partially involves suppression of NF-kappa-B.

1. Finkelman, FD. et al. (2004) Immunological reviews 201, 139-55. PMID: 15361238
2. Zhang, M. et al. (2021) Journal of immunology (Baltimore, Md. : 1950) 207, 3070-3080. PMID: 34789557
3. Mayer, JU. et al. (2021) Nature immunology 22, 1538-1550. PMID: 34795444
4. Takeda, K. et al. (1996) Journal of immunology (Baltimore, Md. : 1950) 157, 3220-2. PMID: 8871614
5. Duffen, J. et al. (2018) Journal of immunology (Baltimore, Md. : 1950) 200, 1347-1359. PMID: 29305434
NoteFor research use only
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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