ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
种属
Mus musculus (Mouse)
性质
Recombinant
内毒素水平
Please contact with the lab for this information.
纯度
>90% as determined by SDS-PAGE.
状态
Lyophilized
保存溶液
Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.
Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
重悬
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
运输
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
稳定性和存储
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名
Annexin A1, Annexin Ac2-26, Annexin I, Annexin-1, Anx1, Anxa1, Calpactin II, Calpactin-2, Chromobindin-9, Lipocortin I, Lpc-1, Lpc1, Phospholipase A2 inhibitory protein, p35
背景
Annexin A1 is a ~38 kDa protein. Plays important roles in the innate immune response as effector of glucocorticoid-mediated responses and regulator of the inflammatory process. Has anti-inflammatory activity. Plays a role in glucocorticoid-mediated down-regulation of the early phase of the inflammatory response. Contributes to the adaptive immune response by enhancing signaling cascades that are triggered by T-cell activation, regulates differentiation and proliferation of activated T cells. Promotes the differentiation of T cells into Th1 cells and negatively regulates differentiation into Th2 cells.
1. Hannon, R. et al. (2003) FASEB journal : official publication of the Federation of American Societies for Experimental Biology 17, 253-5. PMID: 12475898
2. D'Acquisto, F. et al. (2007) European journal of immunology 37, 3131-42. PMID: 17948261
3. Patel, DM. et al. (2011) Journal of cell science 124, 578-88. PMID: 21245195
