

| 货号 | HD777012 |
|---|---|
| 品牌 | abinScience |
| 描述 |
Recombinant Human CBFA2T2 Protein, N-His (HD777012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE..
Highlights
|
| 表达系统 | E. coli |
| Accession号 | O43439 |
| 蛋白长度 | Ala109-Asn213 |
| 应用 | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 种属 | Homo sapiens (Human) |
| 性质 | Recombinant |
| 内毒素水平 | Please contact with the lab for this information. |
| 纯度 | >90% as determined by SDS-PAGE. |
| 预测分子量 | 14.19 kDa |
| 状态 | Lyophilized |
| 保存溶液 | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 重悬 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 运输 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 别名 | CBFA2T2, EHT, ETO homologous on chromosome 20, MTG8-like protein, MTG8-related protein 1, MTGR1, Myeloid translocation-related protein 1, Protein CBFA2T2, p85 |
| 背景 | Protein CBFA2T2 is a ~67 kDa protein. Transcriptional corepressor which facilitates transcriptional repression via its association with DNA-binding transcription factors and recruitment of other corepressors and histone-modifying enzymes. Via association with PRDM14 is involved in regulation of embryonic stem cell (ESC) pluripotency. Involved in primordial germ cell (PCG) formation. Stabilizes PRDM14 and OCT4 on chromatin in a homooligomerization-dependent manner. Can repress the expression of MMP7 in a ZBTB33-dependent manner. 1. Davis, JN. et al. (2003) Gene 303, 1-10. PMID: 12559562 2. Rossetti, S. et al. (2004) Genomics 84, 1-9. PMID: 15203199 3. Tu, S. et al. (2016) Nature 534, 387-90. PMID: 27281218 4. Barrett, CW. et al. (2012) PloS one 7, e51205. PMID: 23251453 |
| Note | For research use only |

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