

| 货号 | HD802012 |
|---|---|
| 品牌 | abinScience |
| 描述 |
Recombinant Human CHD6 Protein, N-His (HD802012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE..
Highlights
|
| 表达系统 | E. coli |
| Accession号 | Q8TD26 |
| 蛋白长度 | Tyr455-Arg682 |
| 应用 | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 种属 | Homo sapiens (Human) |
| 性质 | Recombinant |
| 内毒素水平 | Please contact with the lab for this information. |
| 纯度 | >90% as determined by SDS-PAGE. |
| 预测分子量 | 29.01 kDa |
| 状态 | Lyophilized |
| 保存溶液 | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 重悬 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 运输 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 别名 | ATP-dependent chromatin remodeler CHD6, CHD-6, CHD5, CHD6, Chromo domain-containing protein 6, EC:3.6.4.-, KIAA1335, RIGB, Radiation-induced gene B protein |
| 背景 | ATP-dependent chromatin remodeler CHD6 is a ~305 kDa protein. ATP-dependent chromatin-remodeling factor. Regulates transcription by disrupting nucleosomes in a largely non-sliding manner which strongly increases the accessibility of chromatin; nucleosome disruption requires ATP. Activates transcription of specific genes in response to oxidative stress through interaction with NFE2L2. 1. Lutz, T. et al. (2006) FEBS letters 580, 5851-7. PMID: 17027977 2. Manning, BJ. et al. (2017) The Journal of biological chemistry 292, 11927-11936. PMID: 28533432 |
| Note | For research use only |

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