ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
种属
Homo sapiens (Human)
性质
Recombinant
内毒素水平
Please contact with the lab for this information.
纯度
>90% as determined by SDS-PAGE.
预测分子量
21.16 kDa
状态
Lyophilized
保存溶液
Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.
Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
重悬
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
运输
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
稳定性和存储
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名
ADAP, Adhesion and degranulation promoting adaptor protein, FYB, FYB-120/130, FYB1, FYN-T-binding protein, FYN-binding protein 1, SLAP-130, SLAP130, SLP-76-associated phosphoprotein, p120/p130
背景
FYN-binding protein 1 is a ~85 kDa protein. Acts as an adapter protein of the FYN and LCP2 signaling cascades in T-cells. May play a role in linking T-cell signaling to remodeling of the actin cytoskeleton. Modulates the expression of IL2. Involved in platelet activation. Prevents the degradation of SKAP1 and SKAP2.
1. Krause, M. et al. (2000) The Journal of cell biology 149, 181-94. PMID: 10747096
2. Kliche, S. et al. (2006) Molecular and cellular biology 26, 7130-44. PMID: 16980616
3. Huang, Y. et al. (2005) The Journal of biological chemistry 280, 23576-83. PMID: 15849195
