ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
种属
Homo sapiens (Human)
性质
Recombinant
内毒素水平
Please contact with the lab for this information.
纯度
>90% as determined by SDS-PAGE.
预测分子量
30.26 kDa
状态
Lyophilized
保存溶液
Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.
Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
重悬
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
运输
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
稳定性和存储
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
Deoxyguanosine kinase, mitochondrial is a ~32 kDa protein. Phosphorylates deoxyguanosine and deoxyadenosine in the mitochondrial matrix, with the highest efficiency for deoxyguanosine. In non-replicating cells, where cytosolic dNTP synthesis is down-regulated, mtDNA synthesis depends solely on DGUOK and TK2. Phosphorylates certain nucleoside analogs. Widely used as target of antiviral and chemotherapeutic agents.
1. Saada, A. et al. (2001) Nature genetics 29, 342-4. PMID: 11687801
2. Mousson de Camaret, B. et al. (2007) The Biochemical journal 402, 377-85. PMID: 17073823
3. Ronchi, D. et al. (2012) Brain : a journal of neurology 135, 3404-15. PMID: 23043144
4. Johansson, M. et al. (1996) Proceedings of the National Academy of Sciences of the United States of America 93, 7258-62. PMID: 8692979
5. Wang, L. et al. (1996) FEBS letters 390, 39-43. PMID: 8706825
