

| 货号 | HD917012 |
|---|---|
| 品牌 | abinScience |
| 描述 |
Recombinant Human SREBF2 Protein, N-His (HD917012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE..
Highlights
|
| 表达系统 | E. coli |
| Accession号 | Q12772 |
| 蛋白长度 | Arg569-Arg773 |
| 应用 | ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress |
| 种属 | Homo sapiens (Human) |
| 性质 | Recombinant |
| 内毒素水平 | Please contact with the lab for this information. |
| 纯度 | >90% as determined by SDS-PAGE. |
| 状态 | Lyophilized |
| 保存溶液 | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA. |
| 重悬 | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| 运输 | In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise. |
| 稳定性和存储 | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt. |
| 别名 | BHLHD2, Class D basic helix-loop-helix protein 2, Processed sterol regulatory element-binding protein 2, SREBF2, SREBP-2, SREBP2, Sterol regulatory element-binding protein 2, Sterol regulatory element-binding transcription factor 2, Transcription factor SREBF2, bHLHd2 |
| 背景 | Sterol regulatory element-binding protein 2 is a ~123 kDa protein. Precursor of the transcription factor form (Processed sterol regulatory element-binding protein 2), which is embedded in the endoplasmic reticulum membrane. Low sterol concentrations promote processing of this form, releasing the transcription factor form that translocates into the nucleus and activates transcription of genes involved in cholesterol biosynthesis. 1. Xu, D. et al. (2020) Nature 580, 530-535. PMID: 32322062 |
| Note | For research use only |

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