ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
种属
Homo sapiens (Human)
性质
Recombinant
内毒素水平
Please contact with the lab for this information.
纯度
>90% as determined by SDS-PAGE.
预测分子量
29.79 kDa
状态
Lyophilized
保存溶液
Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.
Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
重悬
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
运输
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
稳定性和存储
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名
Chromatin-remodeling ATPase INO80, DNA helicase-related INO80 complex homolog 1, DNA helicase-related protein INO80, EC:3.6.4.-, INO80, INO80 complex subunit A, INO80A, INOC1, KIAA1259, hINO80
背景
Chromatin-remodeling ATPase INO80 is a ~176 kDa protein. ATPase component of the chromatin remodeling INO80 complex which is involved in transcriptional regulation, DNA replication and DNA repair. Binds DNA. As part of the INO80 complex, remodels chromatin by shifting nucleosomes. Regulates transcription upon recruitment by YY1 to YY1-activated genes, where it acts as an essential coactivator. Involved in UV-damage excision DNA repair.
1. Jin, J. et al. (2005) The Journal of biological chemistry 280, 41207-12. PMID: 16230350
2. Bakshi, R. et al. (2006) Biochemical and biophysical research communications 339, 313-20. PMID: 16298340
3. Cai, Y. et al. (2007) Nature structural & molecular biology 14, 872-4. PMID: 17721549
4. Hur, SK. et al. (2010) Cellular and molecular life sciences : CMLS 67, 2283-96. PMID: 20237820
5. Jiang, Y. et al. (2010) Proceedings of the National Academy of Sciences of the United States of America 107, 17274-9. PMID: 20855601
6. Chen, L. et al. (2011) The Journal of biological chemistry 286, 11283-9. PMID: 21303910
