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Human SCNN1B Recombinant Protein (N-His) (HD952012)

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  • 100ug
  • 1mg
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概述
货号HD952012
品牌abinScience
描述
Recombinant Human SCNN1B Protein, N-His (HD952012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE..
Highlights
  • ●E. coli Expression — High-yield, cost-effective production.
  • ●High Purity — >90% as determined by SDS-PAGE.
表达系统E. coli
Accession号P51168
蛋白长度Ser76-Ala512
应用ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
种属Homo sapiens (Human)
性质Recombinant
内毒素水平Please contact with the lab for this information.
纯度>90% as determined by SDS-PAGE.
预测分子量52.13 kDa
状态Lyophilized
保存溶液 Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.

Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.

重悬Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
运输In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
稳定性和存储Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名Amiloride-sensitive sodium channel subunit beta, Beta-ENaC, Beta-NaCH, ENaC subunit beta, ENaCB, Epithelial Na(+) channel subunit beta, Epithelial sodium channel subunit beta, Nonvoltage-gated sodium channel 1 subunit beta, SCNEB, SCNN1B
背景

Epithelial sodium channel subunit beta is a ~72 kDa protein. This is one of the three pore-forming subunits of the heterotrimeric epithelial sodium channel (ENaC), a critical regulator of sodium balance and fluid homeostasis. ENaC operates in epithelial tissues, where it mediates the electrodiffusion of sodium ions from extracellular fluid through the apical membrane of cells, with water following osmotically. It plays a key role in maintaining sodium homeostasis through electrogenic sodium reabsorption in the kidneys. Additionally, ENaC is essential for airway surface liquid homeostasis, which is crucial for proper mucus clearance.

1. Noreng, S. et al. (2018) eLife 7. PMID: 30251954
2. Noreng, S. et al. (2020) eLife 9. PMID: 32729833
3. McDonald, FJ. et al. (1995) The American journal of physiology 268, C1157-63. PMID: 7762608
4. Goulet, CC. et al. (1998) The Journal of biological chemistry 273, 30012-7. PMID: 9792722
5. Hobbs, CA. et al. (2013) American journal of physiology. Lung cellular and molecular physiology 305, L990-L1001. PMID: 24124190
6. Saxena, A. et al. (2002) The Journal of clinical endocrinology and metabolism 87, 3344-50. PMID: 12107247
NoteFor research use only
图片
参考文献
公式
质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)
填写 质量、浓度、体积中的任意 2 项 + 分子量,自动计算未知值。
质量
=
浓度
×
体积
分子量 *
g/mol
公式
C₁ × V₁ = C₂ × V₂
填写 4 项中的任意 3 项,自动计算未知值。
母液
C₁ (起始浓度)
×
V₁ (起始体积)
=
工作液
C₂ (终浓度)
×
V₂ (终体积)

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