Human OCRL Recombinant Protein (N-His) (HE008012)

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50ug
100ug
1mg

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概述

货号	HE008012
品牌	abinScience
描述	Recombinant Human OCRL Protein, N-His (HE008012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE.. Highlights ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% as determined by SDS-PAGE.
表达系统	E. coli
Accession号	Q01968
蛋白长度	Lys536-Asp901
应用	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
种属	Homo sapiens (Human)
性质	Recombinant
内毒素水平	Please contact with the lab for this information.
纯度	>90% as determined by SDS-PAGE.
预测分子量	44.93 kDa
状态	Lyophilized
保存溶液	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
重悬	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
运输	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名	EC:3.1.3.36, EC:3.1.3.56, EC:3.1.3.86, Inositol polyphosphate 5-phosphatase OCRL, Inositol polyphosphate 5-phosphatase OCRL-1, Lowe oculocerebrorenal syndrome protein, OCRL, OCRL-1, OCRL1, Phosphatidylinositol 3,4,5-triphosphate 5-phosphatase
背景	Inositol polyphosphate 5-phosphatase OCRL is a ~104 kDa protein. Catalyzes the hydrolysis of the 5-position phosphate of phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2) and phosphatidylinositol-3,4,5-bisphosphate (PtdIns(3,4,5)P3), with the greatest catalytic activity towards PtdIns(4,5)P2. Able also to hydrolyze the 5-phosphate of inositol 1,4,5-trisphosphate and of inositol 1,3,4,5-tetrakisphosphate. Regulates traffic in the endosomal pathway by regulating the specific pool of phosphatidylinositol 4,5-bisphosphate that is associated with endosomes. Involved in primary cilia assembly. Acts as a regulator of phagocytosis, hydrolyzing PtdIns(4,5)P2 to promote phagosome closure, through attenuation of PI3K signaling. 1. Kisseleva, MV. et al. (2000) The Journal of biological chemistry 275, 20110-6. PMID: 10764818 2. Schmid, AC. et al. (2004) FEBS letters 576, 9-13. PMID: 15474001 3. Zhang, X. et al. (1995) Proceedings of the National Academy of Sciences of the United States of America 92, 4853-6. PMID: 7761412 4. Zhang, X. et al. (1998) The Journal of biological chemistry 273, 1574-82. PMID: 9430698 5. Nakatsu, F. et al. (2015) The Journal of cell biology 209, 85-95. PMID: 25869668 6. Vicinanza, M. et al. (2011) The EMBO journal 30, 4970-85. PMID: 21971085 7. Coon, BG. et al. (2012) Human molecular genetics 21, 1835-47. PMID: 22228094 8. Luo, N. et al. (2012) Human molecular genetics 21, 3333-44. PMID: 22543976 9. Bohdanowicz, M. et al. (2012) Molecular biology of the cell 23, 176-87. PMID: 22072788
Note	For research use only

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参考文献

产品说明书

Human OCRL Recombinant Protein (N-His).pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

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Human OCRL Recombinant Protein (N-His) (HE008012)

概述

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参考文献

产品说明书

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重组蛋白

抗体

试剂盒

实验相关试剂

Human OCRL Recombinant Protein (N-His) (HE008012)

概述

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参考文献

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