Mouse TRIM72 Recombinant Protein (N-His) (MD364012)

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100ug
1mg

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概述

货号	MD364012
品牌	abinScience
描述	Recombinant Mouse TRIM72 Protein, N-His (MD364012) expressed in E. coli. Purity: >90% as determined by SDS-PAGE.. Highlights ●E. coli Expression — High-yield, cost-effective production. ●High Purity — >90% as determined by SDS-PAGE.
表达系统	E. coli
Accession号	Q1XH17
蛋白长度	Ala287-Ala477
应用	ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
种属	Mus musculus (Mouse)
性质	Recombinant
内毒素水平	Please contact with the lab for this information.
纯度	>90% as determined by SDS-PAGE.
预测分子量	23.29 kDa
状态	Lyophilized
保存溶液	Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
重悬	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
运输	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名	EC:2.3.2.27, Mg53, Mitsugumin-53, Trim72, Tripartite motif-containing protein 72
背景	Tripartite motif-containing protein 72 is a ~52 kDa protein. Muscle-specific E3 ubiquitin-protein ligase that plays a central role in cell membrane repair by nucleating the assembly of the repair machinery at injury sites. Its ubiquitination activity is mediated by E2 ubiquitin-conjugating enzymes UBE2D1, UBE2D2 and UBE2D3. Acts as a sensor of oxidation: upon membrane damage, entry of extracellular oxidative environment results in disulfide bond formation and homooligomerization at the injury site. This oligomerization acts as a nucleation site for recruitment of TRIM72-containing vesicles to the injury site, leading to membrane patch formation. Probably acts upstream of the Ca(2+)-dependent membrane resealing process. 1. Cai, C. et al. (2009) Nature cell biology 11, 56-64. PMID: 19043407 2. Park, SH. et al. (2023) Nature structural & molecular biology 30, 1695-1706. PMID: 37770719 3. Masumiya, H. et al. (2009) Channels (Austin, Tex.) 3, 6-11. PMID: 19202355 4. Cai, C. et al. (2009) The Journal of biological chemistry 284, 3314-3322. PMID: 19029292
Note	For research use only

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参考文献

产品说明书

Mouse TRIM72 Recombinant Protein (N-His).pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

试剂盒

实验相关试剂

Mouse TRIM72 Recombinant Protein (N-His) (MD364012)

概述

图片

参考文献

产品说明书

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重组蛋白

抗体

试剂盒

实验相关试剂

Mouse TRIM72 Recombinant Protein (N-His) (MD364012)

概述

图片

参考文献

产品说明书

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