ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
种属
Mus musculus (Mouse)
性质
Recombinant
内毒素水平
Please contact with the lab for this information.
纯度
>90% as determined by SDS-PAGE.
预测分子量
13.44 kDa
状态
Lyophilized
保存溶液
Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.
Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
重悬
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
运输
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
稳定性和存储
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名
ACSVL4, Acsvl4, Arachidonate--CoA ligase, EC:6.2.1.-, EC:6.2.1.15, EC:6.2.1.3, FATP-4, Fatp4, Fatty acid transport protein 4, Long-chain fatty acid transport protein 4, Long-chain-fatty-acid--CoA ligase, Slc27a4, Solute carrier family 27 member 4, Very long-chain acyl-CoA synthetase 4
背景
Long-chain fatty acid transport protein 4 is a ~72 kDa protein. Mediates the import of long-chain fatty acids (LCFA) into the cell by facilitating their transport across cell membranes. Appears to be the principal fatty acid transporter in small intestinal enterocytes. Also functions as an acyl-CoA ligase catalyzing the ATP-dependent formation of fatty acyl-CoA using LCFA and very-long-chain fatty acids (VLCFA) as substrates, which prevents fatty acid efflux from cells and might drive more fatty acid uptake. Plays a role in the formation of the epidermal barrier. Required for fat absorption in early embryogenesis.
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2. Zhou, W. et al. (2010) Journal of biomolecular screening 15, 488-97. PMID: 20448275
3. Herrmann, T. et al. (2001) Gene 270, 31-40. PMID: 11404000
4. Herrmann, T. et al. (2003) The Journal of cell biology 161, 1105-15. PMID: 12821645
5. Hall, AM. et al. (2005) The Journal of biological chemistry 280, 11948-54. PMID: 15653672
6. DiRusso, CC. et al. (2005) The Journal of biological chemistry 280, 16829-37. PMID: 15699031
7. Li, S. et al. (2013) The Journal of neuroscience : the official journal of the Society for Neuroscience 33, 3178-89. PMID: 23407971
