ELISA, Immunogen, SDS-PAGE, WB, Bioactivity testing in progress
种属
Mus musculus (Mouse)
性质
Recombinant
内毒素水平
Please contact with the lab for this information.
纯度
>90% as determined by SDS-PAGE.
预测分子量
40.39 kDa
状态
Lyophilized
保存溶液
Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol.
Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
重悬
Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
运输
In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
稳定性和存储
Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名
Putative mitochondrial transporter UCP3, Slc25a9, Solute carrier family 25 member 9, UCP 3, Ucp3, Uncoupling protein 3
背景
Putative mitochondrial transporter UCP3 is a ~33 kDa protein. Putative transmembrane transporter that plays a role in mitochondrial metabolism via an as yet unclear mechanism. Originally, this mitochondrial protein was thought to act as a proton transmembrane transporter from the mitochondrial intermembrane space into the matrix, causing proton leaks through the inner mitochondrial membrane, thereby uncoupling mitochondrial membrane potential generation from ATP synthesis. However, this function is controversial and uncoupling may not be the function, or at least not the main function, but rather a consequence of more conventional metabolite transporter activity.
1. Gong, DW. et al. (2000) The Journal of biological chemistry 275, 16251-7. PMID: 10748195
2. Vidal-Puig, AJ. et al. (2000) The Journal of biological chemistry 275, 16258-66. PMID: 10748196
3. Macher, G. et al. (2018) Biochimica et biophysica acta. Biomembranes 1860, 664-672. PMID: 29212043
4. Cadenas, S. et al. (2002) The Journal of biological chemistry 277, 2773-8. PMID: 11707458
5. Lombardi, A. et al. (2010) The Journal of biological chemistry 285, 16599-605. PMID: 20363757
