GMP Grade Human IL-1 beta/IL-1F2 (Tag Free) (HF943022)

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50ug
100ug
1mg

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概述

货号	HF943022
品牌	abinScience
描述	GMP Grade Human IL-1 beta/IL-1F2 (Tag Free) (HF943022) expressed in E. coli. Purity: >95% as determined by SDS-PAGE. by SDS-PAGE. Highlights ●Recombinant — Consistent lot-to-lot performance. ●High Purity — >95% as determined by SDS-PAGE. by SDS-PAGE for demanding downstream applications. ●Bioactive — Verified biological activity.
表达系统	E. coli
Accession号	P01584
蛋白长度	Ala117-Ser269
应用	ELISA, Functional assay
种属	Homo sapiens (Human)
生物活性	Measured by its ability to induce NF-kB reporter activity in MCF-7 cells. The ED50 is ≤10 pg/ml.
性质	Recombinant
内毒素水平	<0.01 EU/ug
纯度	>95% as determined by SDS-PAGE.
预测分子量	17.4 kDa
状态	Lyophilized
保存溶液	Lyophilized from a 0.22 μm-filtered solution containing 10 mM PB, 5% Trehalose, 0.01% Tween 80, pH 7.4 Please refer to the specific buffer information in the hardcopy of datasheet or the lot-specific COA.
重悬	Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details.
运输	In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.
稳定性和存储	Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at -20 to -80°C for twelve months from the date of receipt.
别名	Catabolin, IL-1 beta, IL1B, IL1F2, Interleukin-1 beta
背景	Interleukin-1 beta (Interleukin-1 beta,IL1B,Catabolin,IL1F2,IL-1 beta) is a ~30 kDa protein. Potent pro-inflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B-cell activation and antibody production, and fibroblast proliferation and collagen production. Promotes Th17 differentiation of T-cells. Synergizes with IL12/interleukin-12 to induce IFNG synthesis from T-helper 1 (Th1) cells. Plays a role in angiogenesis by inducing VEGF production synergistically with TNF and IL6. 1. Tominaga, K. et al. (2000) International immunology 12, 151-60. PMID: 10653850 2. Nakahara, H. et al. (2003) Arthritis and rheumatism 48, 1521-9. PMID: 12794819 3. LaRock, CN. et al. (2016) Science immunology 1. PMID: 28331908 4. Van Damme, J. et al. (1985) Nature 314, 266-8. PMID: 3920526 5. Tian, XX. et al. (2021) International endodontic journal 54, 916-925. PMID: 33377178 6. Xia, S. et al. (2021) Nature 593, 607-611. PMID: 33883744
Note	For research use only.

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参考文献

产品说明书

GMP Grade Human IL-1 beta/IL-1F2 (Tag Free).pdf

公式

质量 (g) = 浓度 (mol/L) × 体积 (L) × 分子量 (g/mol)

填写 质量、浓度、体积中的任意 2 项 + 分子量，自动计算未知值。

质量

浓度

体积

分子量 *

g/mol

公式

C₁ × V₁ = C₂ × V₂

填写 4 项中的任意 3 项，自动计算未知值。

母液

C₁ (起始浓度)

V₁ (起始体积)

工作液

C₂ (终浓度)

V₂ (终体积)

重组蛋白

抗体

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实验相关试剂

GMP Grade Human IL-1 beta/IL-1F2 (Tag Free) (HF943022)

概述

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重组蛋白

抗体

试剂盒

实验相关试剂

GMP Grade Human IL-1 beta/IL-1F2 (Tag Free) (HF943022)

概述

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